Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. Portland / Maine

Best Southern American Restaurants in South Portland

Price
Regions
Areas
Top Rated
Dining Options
Seating options
Accessibility

79 restaurants available nearby

How are Featured results ranked

A photo of Buffalo Wild Wings - South Portland restaurant
1. Buffalo Wild Wings - South Portland
4.0
Excellent(21)
€€€€
• Southern american • South Portland
Booked 1 time today
Since 1982, Buffalo Wild Wings® (or B-Dubs® as our friends call us) has been the ultimate place to watch the game, have a cold beer and eat some great food. At Buffalo Wild Wings, you can always feel comfortable pulling some tables together with your friends and staying as long as you want.
A photo of Sea Dog Brewing Co. - So. Portland restaurant
2. Sea Dog Brewing Co. - So. Portland
4.3
Awesome(40)
€€€€
• Southern american • Portland
Using only the most superior ingredients in their beer and plates, Sea Dog Brewing Company in South Portland serves up innovative pub fare with an original touch. All beer sold at Sea Dog Brewing Company are hand-crafted, as is the American pub cuisine, adding to the restaurant's authenticity. The restaurant offers ample seating for most party sizes, and boasts a private function room available to reserve for group gatherings. Sea Dog Brewing Company offers a selection of pub comfort favorites like Maine lobster bisque with huge chunks of lobster meat, steak tip poutine, and plenty of shareable appetizers. In addition, the menu features other popular dishes like fish and chips and blackened haddock tacos, as well as vegetarian and gluten free options.The friendly staff at Sea Dog Brewing on Western Avenue in South Portland would love to take care of you while you await your flight at PWM, on your lunch break from work, or for weekend brunch with family and friends!
A photo of Scales restaurant
Icon
3. Scales
4.9
Exceptional(7851)
€€€€
• Southern american • Portland
Booked 133 times today
Scales in Portland offers an exemplary American dining experience with a special nod to New England's culinary heritage. Nestled on Maine Wharf, this restaurant combines traditional American seafood delicacies with modern touches, all while providing diners with a breathtaking view of a bustling Maine harbor. Guests rave about the "phenomenal service" and "amazing food," highlighting dishes like the halibut and seafood stew as unforgettable. "The best in Portland," Scales consistently delivers with its creative presentations and locally sourced ingredients. Whether you're a local or visiting, Scales is a must-try destination for authentic and high-quality American cuisine.
A photo of Fore Street restaurant
Icon
4. Fore Street
4.8
Exceptional(4747)
€€€€
• Southern american • Portland
Booked 55 times today
Fore Street in Portland's Old Port District is a seafood lover's paradise, renowned for its authentic and high-quality seafood offerings. This celebrated restaurant, “ranked as one of the Top Fifty in the United States by Gourmet Magazine,” is known for its commitment to locally sourced ingredients. Diners rave about the freshness and richness of the seafood, particularly praising the mussels as “the best I’ve ever had.” With a menu that changes daily, reflecting the peak of each ingredient’s season, Fore Street creates a culinary experience that is as fresh as it is unforgettable, making it a must-visit for seafood enthusiasts.
A photo of Ladyfish restaurant
5. Ladyfish
4.4
Awesome(95)
€€€€
• Southern american • Portland
Booked 37 times today
A relaxed, summer-only concept from JordanRubin— Food & Wine 2025 Best New Chef—and partner Marisa Rubin, with award-winning chef, Christine Lau at the helm. Open May-October 2026.“Ladyfish is about celebrating Maine seafood in its most joyful, unfussy form. It’s the kind of food you want to eat all summer long—thoughtful sourcing, simple execution, and a great place to gather. With Chef Christine on board, it’s all of that plus some really interesting flavor profiles that will raise your eyebrows and make you think you’re tasting something familiar, for the very first time.”
A photo of David's Restaurant restaurant
6. David's Restaurant
4.7
Exceptional(4143)
€€€€
• Southern american • Portland
Booked 29 times today
David's Restaurant in Portland is a shining example of authentic American cuisine, celebrated for its "delicious meals and warm, friendly service." Located in the heart of the historic arts district, this local favorite enchants with its eclectic decor and energetic ambiance. Diners rave about its inventive twists on classic American dishes, such as the "incredible meatloaf dinner" and "fresh, creatively prepared seafood." Chef David, voted Portland's best chef in 2021, ensures each dish is a masterpiece, offering options for gluten-free, vegetarian, and vegan diners. With consistent praise for both food and service, it's clear why David's is a must-visit destination for American culinary delights.
A photo of elizabeth restaurant
7. elizabeth
4.6
Exceptional(119)
€€€€
• Southern american • Portland
Booked 13 times today
Elizabeth is an intimate French restaurant and wine bar tucked into Portland's historic Wharf Street. A cherry-red lacquered ceiling, burgundy and zinc bar, and warm candlelight evoke the romance of a Parisian cave à vin, creating an atmosphere that is glamorous, inviting, and quietly decadent.The seasonal menu celebrates Maine's finest ingredients through a distinctly French lens, with dishes such as Oeuf Mayo with smoked salmon caviar, Halibut en Béarnaise with white asparagus and Jonah crab, and Elizabeth's signature Chocolate Soufflé with house-spun hazelnut ice cream.The beverage program features inventive French-inspired cocktails, thoughtfully selected wines by the glass and bottle, and a curated selection of beer, cider, and nonalcoholic offerings.The culinary and beverage teams bring experience from acclaimed restaurants in Chicago and New York.Dollar oyster happy hour + $10 bubbles, Tues-Sat, 4p-5p.Parties of 7+ please email alex@elizabethwharfstreet.com.
A photo of Bissell Brothers restaurant
8. Bissell Brothers
4.8
Exceptional(19)
€€€€
• Southern american • Portland
Booked 12 times today
Bissell Brothers is a family-owned and operated brewery & hospitality destination on Thompson’s Point, just five minutes from downtown Portland, Maine. Alongside our award-winning craft beer, Bissell Brothers Kitchen offers creative, seasonal American cuisine, thoughtfully prepared from the finest local ingredients. Favorites include the Hot Maine Maple Chicken Sandwich, scratch-made Bissell Hot Dog, Jerk Fish Tacos, Farro Salad, and our signature Veggie Burger. Open seven days a week, join us in our family-friendly taproom restaurant or The Garden, our elevated 21+ bar where craft, comfort, and community meet. In addition to our celebrated beer, enjoy house-made hard seltzers and teas, curated cocktails, wine, ciders, and a wide selection of non-alcoholic offerings.Our steadfast dedication to quality and Maine heritage is evident throughout both the kitchen and brewery, distinguishing Bissell Brothers as a premier food and beverage highlight for locals and visitors alike.
A photo of The Grill Room & Bar restaurant
9. The Grill Room & Bar
4.5
Awesome(1327)
€€€€
• Southern american • Portland
Booked 24 times today
Opened by local chef/owner Harding Lee Smith & located in the heart of the historic Old Port, The Grill Room & Bar, has been a staple in Portland's burgeoning food since 2008. An open kitchen concept featuring locally sourced french inspired plates makes this "urban steakhouse" a distinctive dining experience for any occasion. Enjoy Chef Entrees or the A la Carte Menu. In addition, The Grill Room Bar offers a generous variety of wine, local beer & handcrafted cocktails. Stop in from 4-6pm Tuesday - Saturday for Happy Hour Small Bites & Drinks. The patio is pet friendly and is available for seating on a weather dependent basis. The Grill Room is joined by Portland sister restaurants The Front Room & Corner Room & The Mountain Room & Last Run Room @ Sunday River Ski Resort... Walk-ins are welcome although reservations are highly recommended.Large parties are encouraged to call the restaurant directly @ 207 774 2333 or email thegrillroom@gmail.com for reservation needs.
A photo of Thames Landing restaurant
10. Thames Landing
4.4
Awesome(206)
€€€€
• Southern american • Portland
Booked 40 times today
Thames Landing offers an exquisite seafood experience in the heart of Portland, making it a must-visit for seafood enthusiasts. Known for its modern New England fare, the restaurant delights with dishes like the perfectly seasoned lobster rolls and the mouthwatering mussel appetizer, celebrated for its "most delicious sauce." Diners rave about the "lobster mushroom risotto," describing it as a standout dish that embodies authenticity and fresh, local flavors. With its airy dining room and cozy garden patio, Thames Landing provides not only exceptional seafood but also a welcoming atmosphere, ensuring a memorable meal with every visit.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
More
Our sites
Businesses
  • Restaurant Management Solutions
  • Restaurant Booking Software
  • Restaurant Marketing Software
  • Restaurant Event Software
  • OpenTable For Restaurants
  • OpenTable For Restaurant Groups
  • Restaurant Resources
  • OpenTable Pricing & Plans
Join us on
  • Privacy policy
  • Terms of Use
  • Impressum
  • Cookies and Interest-Based Ads
  • Accessibility Statement
  • Cookie Preferences
Copyright © 2026 OpenTable International Ltd. Alphabeta Building, 14-18 Finsbury Square, London EC2A 1AH - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo